BIOPURE Reference Materials Mycotoxins – Toxins

Standaarden; Single Calibrant Solutions en Mixen
Food Risk Management biedt het volledige RomerLabs assortiment referentie materiaal & ‘Interne Kalibratie Standaarden’ (IS ) aan voor HPLC en LC-MS/MS.
o.a. voor mycotoxinen onder de merknaam Biopure® .

Het BIopure assortiment bevat een brede range referentie materialen / standaarden zowel in vaste,- als vloeibare vorm en mix oplossingen.

Specifiek voor LC-MS/MS methode heeft Biopure® een exclusieve reeks internal Fully Stable Isotope Labelled standaarden in haar assortiment.

Certified Reference Material (CRM):

Stable Isotopic
Labelled Mycotoxin
Liquid Calibrants:

Isotopic Labelled Calibrant <lees meer >



Certified Reference Material 2018

BIOPURE productlist 2017

 Kijk voor verdere product
informatie ook eens op de
RomerLabs website


BIOPURE: referentie standaarden mycotoxinen.

nnnA reference material one or more of whose property values are certified by a procedure which establishes its traceability to an accurate realization of the unit in which the property values are expressed, and for which each certified value is accompanied by an uncertainty at a stated level of confidence.

The 3 Keys for high quality RMs“:

  1. Traceability
  2. Certified Value
  3. Uncertainty Statement

Single Calibrant Solutions
ISO Guide 34 – Certified Reference Materials
Mycotoxin Calibrant Mixtures
Solid Mycotoxin Standards
Stable Isotopic Labeled Mycotoxin Liquid Calibrants


Full traceability is a key factor in audit situations. Certified reference materials, accompanied by full and clear documentation, are one way to accomplish this.

Many terms describe reference standards in analytical methods, like reference materials, certified reference materials, calibrator, standard, etc. Certified reference materials are defined as reference materials characterized by metrological traceability, a certified value and an uncertainty budget. It complies with all requirements of ISO 17025, GLP, etc. and comes with complete documentation on:


  • purity assessment of the raw material
  • traceability back to national standards
  • measurement uncertainty and its calculation
  • a homogeneity study
  • a long- and short-term stability study
  • description of intended use

Certified reference materials are intended for the verification of in-house standards such as reference materials routinely used in the lab. They are used for the calibration of equipment especially in ISO 17025 accredited testing laboratories where traceability and high quality of results are of great importance.

The table below illustrates the differences between a reference material and a certified reference material for BiopureTM calibrants. A certified reference material has full proof of traceability which is important for audit situations. Furthermore, it has a stated uncertainty and full transparency of the preparation and certification process.

Only an accredited institution which strictly follows ISO Guide 34 is allowed to issue certified reference materials. ISO Guide 34 defines the “General requirements for the competence of reference material producers” and is built upon ISO 17025, including additional technical requirements for certified reference materials.

Bijgeleverde analyse certificaten van de BIOPURE oplossingen:ffff

Certified Value: For a CRM, the value that appears in the certificate accompanying the material.

Omvat o.a.:

  • Detailed name of the material
  • Producer & producers code
  • General description of material & expiry date
  • Intended use
  • Instructions for proper use
  • Instructions for storage
  • Certified property value(s) + statement of uncertainty
  • Documentation of traceability
  • Method(s) used to obtain property values


Ergot Alkaloïde standaarden

ergotsErgot alkaloids are mycotoxins produced by fungi of all members of the Claviceps species, most important in terms of frequency of occurence C. purpurea.

These fungi are able to produce a wintering body, also known as sclerotium. Such structures are mainly found on rye, wheat and triticale. Sclerotia contain different classes of alkaloids, the most prominent being:

ergometrine, ergotamine, α-Ergosine, ergocristine, α-Ergocryptine and ergocornine
< Brochure Ergot’s 2016 >

Food Risk Management & RomerLabs BIOPURE products:

In 2016 is er door de BIOPURE productie afdeling binnen RomerLabs enkele ISO Guide 34 gecertificeerde standaarden aan het mycotoxinen assortiment referentie standaarden toegevoegd.

Certified Reference Material BIOPURE:

Article: Nivalenol in Acetonitrile

Offering significant advantages

  • Protect your business and your brand
  • Complete chain of traceability – fully documented

Increased reliability and accuracy of measurement results

  • Increasing confidence in results
  • Stability & homogeneity tested according to ISO Guide 34
  • Certificate of analysis and full certification report available

Complying with external standard

  • Comply with all requirements in ISO 17025, GLP etc.
  • Highest possible quality standard for reference material producers
  • Full documentation of traceability, measurement uncertainty etc.
  • For successful audits and accreditations
  • Validation of analytical methods
Certificate of Analyses:CRM001

<klik op afbeelding voor de pdf. COA- deoxynivalenol- DON>



Overzicht BIOPURE standaarden.
<klik op afbeelding voor de pdf. BIOPURE productlist 2016>


Wenst u meer technische details te ontvangen van het BIOPURE assortiment standaarden of de individuele componenten gelieve contact met Food Risk Management op te nemen. Het productmanagment team BIOPURE bij RomerLabs staan u graag te woord.

Wij sturen u graag verdere technische informatie over de RomerLabs BIOPURE standaarden door. De FRM 2018 prijslijst is vrijblijvend opvraagbaar.
prijsNeem contact op met Food Risk Management via :